Cigna LifeSOURCE secures written agreements with select independent transplant facilities that are nationally recognized for their quality care. We have more than 170 facilities in our network. Each Cigna LifeSOURCE program is carefully chosen to participate in the Cigna LifeSOURCE Transplant Network and must continue to meet our established quality standards. Our transplant programs are approved at one of the following levels of participation:

1. Designated Level: To be approved to be in our top tier Designated Level, each solid organ transplant program is reviewed and must be ranked in the top four quintiles in their region based on the  Relative Performance Index (RPI). All programs must maintain minimum volumes, waitlist transplant rate, waitlist mortality, patient and graft survival outcomes and accreditations to be listed as Designated. Each bone marrow/stem cell transplant must also meet or exceed the minimum 100-day outcomes. Designation status is also be dependent on a market check to confirm the rates for each program are competitively priced relative to equivalent programs in the region and/or market. Please note, not every transplant program at a Cigna LifeSOURCE participating facility may meet all the Designated level minimum guidelines at a given time.

2. Supplemental Level: Programs not meeting the Designated level are eligible for consideration as a Supplemental program. This solution was developed to provide clients access to certain transplant programs outside of the Designated level. These programs do not meet the stringent Designated level standards of transplant outcomes and/or cost-efficiency, but they must achieve and maintain the Centers for Medicaid and Medicare (CMS) certification for solid organs, and the Foundation for Accreditation of Cellular Therapy (FACT) and National Marrow Donor Program (NMDP) accreditation for bone marrow/stem cell transplants. In the event the certifications and/or accreditations are in jeopardy or have been suspended for any reason, the program may lose its participation level status and will no longer be a participating program in the Cigna LifeSOURCE Transplant Network.

3. Ventricular Assist Device (VAD) Network: The VAD Network was created to fill the need for people who are determined to not be a candidate for heart transplant, but are a candidate for a Ventricular Assist Device used for Destination Therapy. The heart transplant program must be a participating program in the Cigna LifeSOURCE Transplant Network in order for the VAD program to be included in the Cigna LifeSOURCE VAD Network. The VAD program must obtain and maintain CMS certification for Destination Therapy and hold accreditation by the Joint Commission or DNV Health Care. The programs currently participating in the VAD Network can be found on the transplant program directory/listings.

4. Advanced Cellular Therapy (ACT) Network: The ACT Network, which includes includes Car-T cell therapy, was created to provide access to providers who perform Car-T infusions. The providers must achieve the Foundations for the Accreditation of Cellular Therapy (FACT) for both bone marrow/stem cell therapy and immune effector cell therapy. The Car-T program approval is contingent upon the transplant center’s bone marrow/stem cell transplant program as a participating program in the Cigna LifeSOURCE Transplant Network. Please see our Car-T flyer for more helpful information.

Our programs are all reviewed annually. This may result in a program being moved from one level of participation to another, or being removed altogether from participating in the Cigna LifeSOURCE Transplant Network. For additional information, please review our Cigna LifeSOURCE Guidelines for Participation, as well as the Cigna LifeSOURCE Relative Performance Index Methodology paper.

Interrelationships in the World of Solid Organ Transplantation

Interrelationships in the World of Bone Marrow Transplantation

Zones of Transplantation

Find a Facility:

Cigna LifeSOURCE Transplant Network

Cigna LifeSOURCE Advanced Cellular Therapy Programs

Cigna LifeSOURCE Medicare Advantage Addendums NAC